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American Society of Microbiology ABMM Sample Questions (Q45-Q50):
NEW QUESTION # 45
For epidemiological tracking and outbreak investigations of Clostridioides difficile infection (CDI), which molecular typing method based on PCR amplification targeting repetitive elements within the pathogenicity locus (PaLoc) has historically been widely used and designated by specific nomenclature (e.g., NAP1/BI
/027)?
- A. PCR Ribotyping
- B. Whole-genome sequencing (WGS) SNP analysis
- C. Multilocus sequence typing (MLST)
- D. Pulsed-field gel electrophoresis (PFGE)
Answer: A
NEW QUESTION # 46
A patient develops a localized skin infection characterized by a painless, progressive ulcer with raised, indurated margins. Microscopic examination of tissue scrapings reveals amastigotes within macrophages. The patient reports recent travel to Central or South America. The MOST likely diagnosis is cutaneous:
- A. Sporotrichosis
- B. Myiasis
- C. Leishmaniasis
- D. Chromoblastomycosis
Answer: C
NEW QUESTION # 47
A previously healthy 28-year-old female develops a severe, watery diarrhea after attending a picnic where she consumed potato salad that had been left unrefrigerated for several hours. Stool culture reveals numerous Gram-positive bacilli. Further biochemical testing shows the organism is beta-hemolytic on blood agar and produces a heat-stable enterotoxin. The MOST likely causative agent is:
- A. Bacillus cereus
- B. Clostridium difficile
- C. Vibrio cholerae
- D. Staphylococcus aureus
Answer: A
NEW QUESTION # 48
During an outbreak of norovirus gastroenteritis in a nursing home, environmental swabs are collected to identify the source of the infection. Which of the following methods would be MOST appropriate for detecting norovirus in these samples?
- A. Gram staining and microscopy
- B. Enzyme-linked immunosorbent assay (ELISA) for viral antigens
- C. Reverse transcription-polymerase chain reaction (RT-PCR)
- D. Culture on human embryonic kidney (HEK) cells
Answer: C
NEW QUESTION # 49
A patient with HIV infection and a low CD4+ T-cell count presents with fever, weight loss, and cough. Chest X-ray shows diffuse interstitial infiltrates. Sputum induction reveals oval yeast cells with narrow-based budding. The MOST likely diagnosis is:
- A. Histoplasmosis
- B. Pneumocystis pneumonia
- C. Tuberculosis
- D. Cryptococcosis
Answer: A
NEW QUESTION # 50
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